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This study aims to evaluate the trend of Internet-based sex-seeking behavior of MSM and its impact on HIV prevalence, the distribution of HIV subtype strains, and transmitted drug resistance rates.

A serial cross-sectional study was conducted from 2009 to 2014.

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The prevalence of HIV in China continues to increase, with rates in Chinese MSM increasing from 0.9% to 7.3% from 2003 to 2013 [1].

Out of the newly reported HIV/AIDS cases in China in 2015, 28.3% were from the MSM population [2], while in 2011, MSM only accounted for 13.7% of newly reported cases [3].

The Institutional Review Boards of the First Affiliated Hospital of CMU approved the study protocol and informed consent forms.

The Voluntary Counseling and Testing (VCT) clinic of the First Affiliated Hospital of China Medical University (CMU) in Shenyang was chosen as the study site.

With the development of Internet and mobile technology, the ways of socializing and seeking homosexual partners have changed dramatically with MSM.

More and more MSM use Internet- or mobile-based geosocial networking (GSN) applications to socialize and seek partners.

Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China Received 7 September 2016; Revised 16 November 2016; Accepted 1 December 2016Academic Editor: Lei Zhang Copyright © 2016 Shi Pan et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

HIV prevalence is still rapidly increasing among Chinese men who have sex with men (MSM).

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